Does disulfiram have a role in alcoholism treatment today?
نویسندگان
چکیده
منابع مشابه
Disulfiram Treatment of Alcoholism
P to the completion of this welldesigned scientific study, which was conducted at nine Veterans Administration Medical Centers, the medication disulfiram (Antabuse®) was controversial in the treatment of alcoholism. The controversy over its efficacy was rooted in the lack of sophisticated scientific data on which to base its effectiveness. Fuller and colleagues used stateoftheart clinical r...
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متن کاملA Case of Psychosis in Disulfiram Treatment for Alcoholism
Background. Disulfiram, a drug used in the treatment of alcohol dependence, is an inhibitor of dopamine- β -hydroxylase causing an increase in the concentration of dopamine in the mesolimbic system. In addition to the physical symptoms associated with concomitant use of alcohol, disulfiram may lead to adverse events, when used alone, including psychosis. Aims. To report a case of a rare complic...
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Supervised intake of the alcohol deterrent (AD) disulfiram has proven to be an effective adjunct to biopsychosocial alcoholism therapy for more than 60 years. This article summarizes disulfiram literature between 1937 and 2000 and reviews 13 clinical trials of disulfiram in alcoholism treatment from the years 2000 to 2008. After giving an update of general safety issues and recent case reports ...
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Trace element status was ascertained in 19 alcoholic patients under long-term treatment with disulfiram and in 12 alcoholic patients treated for the first time; the latter group was re-examined after four weeks of treatment. Both groups were compared to matched controls with a moderate alcohol intake. The copper/zinc ratio in serum was increased in the patients under long-term treatment, and a ...
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ژورنال
عنوان ژورنال: Addiction
سال: 2004
ISSN: 0965-2140,1360-0443
DOI: 10.1111/j.1360-0443.2004.00597.x